Thermo Fisher Scientific Phospho-STAT2 (Tyr631) Polyclonal Antibody
Rabbit 유래 Phospho-STAT2 (Tyr631) 폴리클로날 항체로, 인산화된 STAT2 단백질 검출에 사용됩니다. IHC(P)에서 1:50–1:100 희석으로 적용 가능하며, 액상 형태로 제공됩니다. 연구용으로만 사용되며 -20°C에 보관합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human STAT2 around the phosphorylation site of Tyr631 (Q-P-YP-T-K) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556274 |
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, then form homo- or heterodimers that translocate to the cell nucleus to act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), acting as a transactivator but lacking direct DNA-binding ability. Transcription adaptor P300/CBP (EP300/CREBBP) interacts specifically with STAT2 and is thought to be involved in blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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