Thermo Fisher Scientific Phospho-AKT Pan (Tyr315, Tyr316, Tyr312) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phosphorylated AKT1/2/3 at Tyr315/316/312. Suitable for IHC and peptide-ELISA. High specificity for phospho-AKT signaling studies. Supplied as liquid, 1 mg/mL, stored at -20°C.
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Thermo Fisher Scientific Phospho-AKT Pan (Tyr315, Tyr316, Tyr312) Polyclonal Antibody
Applications and Tested Dilutions
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:100
- Peptide-ELISA (pep-ELISA): 1:20,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human AKT1/2/3 around Tyr315/316/312 (P-E-YP-L-A) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556276 |
Target Information
AKT, also known as protein kinase B (PKB) or RAS-alpha, is a serine/threonine kinase involved in regulating metabolism, cell survival, and growth. It is activated by insulin, PI3K, IGF1, and various growth factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of targets such as forkhead transcription factors and caspase-9. The AKT pathway is a major target in cancer drug discovery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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