Thermo Fisher Scientific APBA1 Polyclonal Antibody
APBA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간·생쥐·랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 항체로, 뇌 조직에서의 단백질 연구에 유용.
- 판매단위
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5 µg/mL |
| Immunohistochemistry (IHC) | 20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 19 amino acid synthetic peptide near the amino terminus of human APBA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551770 |
Product Specific Information
- Suggested positive control: rat brain tissue lysate
- PA5-34418 can be used with blocking peptide PEP-1460.
Target Information
The munc-18 interacting protein (Mint) family consists of evolutionarily conserved adaptor proteins involved in membrane transport and organization. In mammals, three isoforms—Mint1, Mint2, and Mint3—exist.
Mint1 and Mint2 are expressed primarily in the brain and interact with Munc18, a key component of synaptic vesicle fusion. Mint3, expressed in most tissues at low levels in brain and testis, interacts with amyloid precursor protein (APP) via PTB and PDZ domains, potentially regulating APP transport, endocytosis, and metabolism. Abnormal APP metabolism is associated with early-onset Alzheimer’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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