Thermo Fisher Scientific EDEM2 Polyclonal Antibody
EDEM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. ER-associated degradation 연구용으로 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 399–578 of human EDEM2 (NP_060687.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.96 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914107 |
Product Specific Information
- Positive test controls include: A375, HepG2.
- Immunogen sequence:
SIEKISKVEC GFATIKDLRD HKLDNRMESF FLAETVKYLY LLFDPTNFIH
NNGSTFDAVI TPYGECILGA GGYIFNTEAH PIDPAALHCC QRLKEEQWEV
EDLMREFYSL KRSRSKFQKN TVSSGPWEPP ARPGTLFSPE NHDQARERKP
AKQKVPLLSC PSQPFTSKLA LLGQVFLDSS
Target Information
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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