Thermo Fisher Scientific CD122 Polyclonal Antibody
Thermo Fisher Scientific의 CD122 Polyclonal Antibody는 마우스 IL2RB C-말단 서열을 기반으로 제작된 Rabbit IgG 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB (503–539aa NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746611 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:
- Low affinity form: Monomer of the alpha subunit; not involved in signal transduction.
- Intermediate affinity form: Alpha/beta heterodimer; participates in receptor-mediated endocytosis and mitogenic signal transduction.
- High affinity form: Alpha/beta/gamma heterotrimer; also involved in signal transduction.
The CD122 gene encodes the beta subunit, a type I membrane protein. Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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