Thermo Fisher Scientific IL-3 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Most of these functions are enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity at the amino acid level, and the bioactivity of IL-3 is highly species specific (e.g., human IL-3 has no activity on mouse cells).
IL-3 supports proliferation of various hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis. It has also been shown to possess neurotrophic activity and may be associated with neurologic disorders.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.