Thermo Fisher Scientific NAIP Polyclonal Antibody
NAIP 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot 및 면역세포염색(ICC/IF)에 적합하며, 인간 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS에 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1.0 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151863 |
Product Specific Information
- Suggested positive control: PC-3 cell lysate
- Recommended blocking peptide: PEP-0182
Target Information
Neuronal apoptosis inhibitor protein (NAIP) is the first human inhibitor of apoptosis protein (IAP) identified, discovered through its association with spinal muscular atrophy.
Members of the IAP family contain one to three baculovirus IAP repeat (BIR) domains that mediate interactions with caspases (e.g., caspase-3, -7, -9) and TRAF family members.
Unlike other IAPs, NAIP requires ATP to bind caspase-9 and is not inhibited by Smac/DIABLO, indicating a unique regulatory mechanism.
Although only one human NAIP protein is identified, shorter NAIP mRNA transcripts have been reported.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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