Thermo Fisher Scientific cIAP1 Polyclonal Antibody
cIAP1 및 cIAP2를 모두 검출하는 Rabbit Polyclonal Antibody. Western blot, IHC(P), IHC(PFA)에서 사용 가능. 항원 친화 크로마토그래피로 정제된 1 mg/mL 액상 시약. PBS 버퍼 및 0.02% sodium azide 포함, 2–8°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 20 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to 14 amino acids at the C-terminus of human c-IAP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 2–8°C up to 3 months; long-term at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154367 |
Product Specific Information
- Detects both c-IAP1 and c-IAP2.
- Suggested positive control: human lung tissue lysate.
- Compatible blocking peptide: PEP-0185.
Target Information
The encoded protein belongs to a family that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors (TRAF1 and TRAF2), likely interfering with activation of ICE-like proteases. It prevents apoptosis induced by serum deprivation and menadione, a potent free radical inducer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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