Thermo Fisher Scientific CD26 Monoclonal Antibody (OX-61), Biotin
Thermo Fisher Scientific CD26 Monoclonal Antibody (OX-61), Biotin은 Rat CD26 인식을 위한 Mouse IgG2a 단일클론 항체입니다. Western blot, IHC(F), Flow cytometry, Immunoprecipitation에 사용 가능하며, Biotin 결합 형식으로 제공됩니다. Protein G 정제, PBS/BSA buffer에 보관하며 연구용으로 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Flow Cytometry (Flow) | 2.0 µg/1x10^6 cells |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-61 |
| Immunogen | Thoracic duct lymphocytes from a mesenteric lymphodectomised rat |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538937 |
Additional Formats
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV, adenosine deaminase binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, NK cells, and epithelial cells. CD26 participates in T-cell activation, cell adhesion to extracellular matrix (e.g., fibronectin, collagen), and HIV infection. It is identical to adenosine deaminase complexing protein-2 and functions as a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Alterations in CD26 activity are linked to malignant transformation, with increased enzymatic activity correlating with tumor grade. CD26 expression changes have been observed in monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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