Thermo Fisher Scientific Transferrin Receptor Monoclonal Antibody (OX-26), Biotin
Rat 세포의 Transferrin Receptor(CD71)를 인식하는 OX-26 단클론 항체로, Biotin으로 표지됨. IHC(F) 및 Flow Cytometry에 사용 가능하며, Protein G로 정제된 액상 형태. 철 수송 및 적혈구 발달 관련 연구에 적합.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-26 |
| Immunogen | PHA activated lymph node cells of a PVG rat |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538946 |
Additional Formats
Target Information
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is recycled to the cell surface, where neutral pH causes apotransferrin to dissociate. Transferrin receptor is essential for erythrocyte and nervous system development. Serum transferrin receptor (sTfR) is used to detect erythropoietin (EPO) misuse and to diagnose anemias associated with conditions such as rheumatoid arthritis, pregnancy, irritable bowel syndrome, and HIV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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