Thermo Fisher Scientific CD26 Monoclonal Antibody (OX-61), PE
Thermo Fisher Scientific의 CD26 Monoclonal Antibody (OX-61), PE는 Rat 시료에 반응하는 Mouse IgG2a 단일클론 항체로, Flow Cytometry에 적합합니다. PE 형광 표지로 565/576 nm의 Excitation/Emission을 가지며, 4°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1.0 µg / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-61 |
| Immunogen | Thoracic duct lymphocytes from a mesenteric lymphodectomised rat |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538941 |
Additional Formats
- Unconjugated
- Biotin
- FITC
- Custom conjugation available upon request
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV, adenosine deaminase binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and upregulated during T-cell activation, also found on activated B cells, NK cells, and epithelial tissues.
CD26 participates in T-cell activation, cell adhesion to extracellular matrix proteins (fibronectin, collagens), and HIV infection. It functions as a serine exopeptidase, cleaving X-proline dipeptides from the N-terminus of polypeptides.
Alterations in CD26 activity correlate with malignant transformation and tumor severity. Expression changes have been observed in monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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