Thermo Fisher Scientific eIF5B Polyclonal Antibody
Rabbit polyclonal antibody targeting human eIF5B 단백질. Immunocytochemistry(ICC/IF)에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 4°C 단기 보관 또는 -20°C 장기 보관 권장.
- 카탈로그번호
- PA565258
- 판매단위
- pk
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human eIF5B. Recombinant protein control fragment (Product #RP-104713) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662182 |
Product Specific Information
Immunogen sequence:
EGKLLTKSQRE ARARAEATLK LLQAQGVEVP SKDSLPKKRP IYEDKKRKKI PQQLESKEVS ESMELCAAVE VMEQGVPEKE
- Highest antigen sequence identity to the following orthologs: mouse 81%, rat 81%.
Target Information
Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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