Thermo Fisher Scientific ZDHHC16 Polyclonal Antibody
ZDHHC16 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제됨. 인간 단백질에 반응하며, 장기 보관 시 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ZDHHC16. Recombinant protein control fragment (Product # RP-104716) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664326 |
Product Specific Information
Immunogen sequence:
LFREAYAAIEK MKQLDKNKLQ AVANQTYHQT PPPTFSFRER MTHK
Highest antigen sequence identity to the following orthologs:
- Mouse: 62%
- Rat: 62%
Target Information
ZDHHC16 (zinc finger, DHHC-type containing 16), also known as APH2, is a 377 amino acid multi-pass membrane protein localized to the endoplasmic reticulum and containing one DHHC-type zinc finger. It exists as multiple alternatively spliced isoforms, interacts with c-Abl, and catalyzes the conversion of Palmitoyl-CoA and protein-cysteine to S-palmitoyl protein and CoA. Through association with c-Abl, ZDHHC16 may regulate apoptosis.
The ZDHHC16 gene maps to human chromosome 10, which contains over 1,200 genes and comprises nearly 4.5% of the human genome. Mutations in genes on chromosome 10 are associated with several diseases, including Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2, and porphyria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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