Thermo Fisher Scientific RhoBTB1 Polyclonal Antibody
RhoBTB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 40% 글리세롤에 보관됩니다. 인간 시료에 반응하며, 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RhoBTB1. Recombinant protein control fragment (Product #RP-104714). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662255 |
Product Specific Information
Immunogen sequence:
LMECEESPNGS EGACEKEKQS RDFQGRILSV DPEEEREEGP PRIPQADQWK SSNKSLVEAL GLEAEGAVPE
Highest antigen sequence identity to the following orthologs:
- Mouse: 52%
- Rat: 49%
Target Information
RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases.
Members of this subfamily are evolutionarily conserved and characterized by a proline-rich region, a GTPase domain, and two tandem BTB repeats.
RHOBTB1 is expressed at high levels in placenta, stomach, testis, kidney, and skeletal muscle, whereas RHOBTB3 is abundant in neural and cardiac tissues.
RHOBTB1 may play a role in GTPase-mediated signaling and actin filament organization.
Decreased RHOBTB1 expression has been observed in head and neck carcinomas, suggesting a potential tumor suppressor role.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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