ELK Biotechnology Cdc23 rabbit pAb
Cdc23 단백질을 인식하는 토끼 다클론 항체로, WB 및 ELISA에 적합합니다. 인간 APC8 유래 펩타이드로 면역화되었으며, 세포주기 G2/M 전이 관련 연구에 활용됩니다. 인간, 생쥐, 원숭이에 반응하며 -20°C에서 1년 보관 가능합니다.
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Cdc23 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cdc23 rabbit pAb |
| Alternative Names | CDC23; ANAPC8; Cell division cycle protein 23 homolog; Anaphase-promoting complex subunit 8; APC8; Cyclosome subunit 8 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APC8 (AA range: 251–300) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 69 kD |
| Gene ID (Human) | 8697 |
| Human Swiss-Prot No. | Q9UJX2 |
| Cellular Localization | Intracellular, nucleoplasm, anaphase-promoting complex, cytosol |
| Species Reactivity | Human; Mouse; Monkey |
Background
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition.
This protein is a component of the anaphase-promoting complex (APC), composed of eight protein subunits and highly conserved in eukaryotic cells.
APC catalyzes the formation of cyclin B-ubiquitin conjugate responsible for the ubiquitin-mediated proteolysis of B-type cyclins.
This protein and three other members of the APC complex contain the TPR (tetratricopeptide repeat), a domain important for protein–protein interactions.
(Information provided by RefSeq, Jul 2008)
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