ELK Biotechnology BRCAA1 rabbit pAb
BRCAA1 단백질을 인식하는 토끼 폴리클로날 항체로, 인간·생쥐·랫트 시료에 반응. Western blot과 ELISA에 적합하며, 핵 및 세포질 내 BRCAA1 단백질 검출에 유용. -20°C에서 1년 보관 가능.
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제품명
BRCAA1 rabbit pAb
공급업체
ELK Biotechnology
제품 설명
BRCAA1 rabbit polyclonal antibody는 인간 BRCAA1 단백질을 인식하도록 제작된 항체입니다. 이 항체는 세포 내 핵과 세포질에서 발현되는 BRCAA1 단백질 검출에 유용하며, Western blot 및 ELISA 실험에 적합합니다.
스펙 정보
| 항목 | 내용 |
|---|---|
| Product name | BRCAA1 rabbit pAb |
| Alternative Names | ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Breast cancer-associated antigen BRCAA1 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human BRCAA1 (AA range: 761–810) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 148 kDa |
| GeneID (Human) | 51742 |
| Human Swiss-Prot No | Q4LE39 |
| Cellular Localization | Nucleus; Cytoplasm; Cytoplasmic in breast cancer cells |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependent SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. (RefSeq, Jul 2008)
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