ELK Biotechnology ATP5A rabbit pAb
ATP5A 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 ATP5A1 유래 펩타이드로 면역 생성. 미토콘드리아 ATP 합성효소 연구에 적합하며, -20°C에서 1년 보관 가능.
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제품명
ATP5A rabbit pAb
제품 개요
ATP5A 단백질에 특이적인 토끼 폴리클로날 항체입니다. 미토콘드리아 ATP 합성효소의 α-소단위를 인식하며, Western blot, IHC, IF, ELISA 등 다양한 응용에 사용 가능합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | ATP5A rabbit pAb |
| Alternative Names | ATP5A1; ATP5A; ATP5AL2; ATPM; ATP synthase subunit alpha; mitochondrial |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/40000 Other applications not yet tested |
| Immunogen | Synthesized peptide derived from human ATP5A1 (AA range: 201–250) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| Gene ID (Human) | 498 |
| Human Swiss-Prot No. | P25705 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Mitochondrion; Inner membrane; Peripheral membrane protein (matrix side); Cell membrane; Extracellular side. Colocalizes with HRG on T-cell surface (PubMed:19285951). |
Background
This gene encodes a subunit of mitochondrial ATP synthase, which catalyzes ATP synthesis using the proton gradient across the inner mitochondrial membrane during oxidative phosphorylation. ATP synthase consists of two complexes: the soluble catalytic core (F1) and the membrane-spanning proton channel (Fo). The catalytic core includes five different subunits (α, β, γ, δ, ε) in a stoichiometry of 3α, 3β, and one each of the others. The proton channel comprises three main subunits (a, b, c). This gene encodes the α subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified.
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