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ELK Biotechnology Tau (phospho Ser235) rabbit pAb
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Tau 단백질의 Ser235 인산화 부위를 인식하는 토끼 다클론 항체로, WB와 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며, 세포질 및 축삭 부위에서 발현되는 Tau 단백질 연구에 유용합니다. 장기 보관은 -20°C에서 가능합니다.
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- pk
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ELK Biotechnology ES1411-100UL Tau (phospho Ser235) rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES1411-50UL Tau (phospho Ser235) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology Tau (phospho Ser235) rabbit pAb
Tau (phospho Ser235) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Tau (phospho Ser235) rabbit pAb |
| Alternative Names | MAPT; MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Tau around the phosphorylation site of Ser235. AA range: 526-575 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50-85 kD |
| GeneID (Human) | 4137 |
| Human Swiss-Prot No. | P10636 |
| Cellular Localization | Cytoplasm, cytosol; Cell membrane (Peripheral membrane protein, cytoplasmic side); Cytoplasm, cytoskeleton; Cell projection (axon, dendrite); Secreted. Mostly found in the axons of neurons, in the cytosol, and in association with plasma membrane components (PubMed:10747907). Can be secreted; secretion depends on protein unfolding and is facilitated by the cargo receptor TMED10, resulting in translocation from cytoplasm into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). |
| Background | This gene encodes the microtubule-associated protein tau (MAPT), whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer’s disease, Pick’s disease, frontotemporal dementia, cortico-basal degeneration, and progressive supranuclear palsy. (RefSeq, Jul 2008) |
| Species Reactivity | Human; Mouse; Rat |
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