ELK Biotechnology Histone H3 (Mono Methyl Lys80) rabbit pAb
Histone H3 단백질의 Mono Methyl Lys80 부위를 인식하는 rabbit polyclonal antibody. WB와 ELISA에 적합하며, 핵 및 염색체에서 발현되는 히스톤 구조 연구에 활용 가능. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관.
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제품명
Histone H3 (Mono Methyl Lys80) rabbit pAb
제품 개요
Histone H3 단백질의 K80 부위에서 단일 메틸화된 형태를 인식하는 rabbit polyclonal antibody입니다. 히스톤 구조 및 염색질 조절 메커니즘 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | H3K80ME1; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; H3FJ; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; Histone H3.1; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000; ELISA: 1/20000 (다른 응용에는 미시험) |
| Immunogen | Synthesized peptide derived from human Histone H3 around the mono-methylation site of K80 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968, 126961, 333932, 653604, 3020, 3021, 440093 |
| Human Swiss-Prot No | P68431, Q71DI3, P84243, Q6NXT2 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Approximately 146 bp of DNA wraps around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone (H1) with DNA between nucleosomes, forming higher-order chromatin structures. This gene is intronless and encodes a replication-dependent histone, a member of the histone H3 family. Transcripts from this gene lack polyA tails, containing instead a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22-p21.3. (RefSeq, Aug 2015)
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