Thermo Fisher Scientific Phospho-MST3 (Thr18) Polyclonal Antibody
MST3 단백질의 Thr18 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. WB, IHC(P), ICC/IF에 적합하며, Human, Mouse, Rat 시료에 반응. 1 mg/mL 농도의 액상 형태로, PBS(50% glycerol, 0.02% sodium azide) 용액에 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STK24 (Accession Q9Y6E0), corresponding to amino acid residues around phosphorylated Thr18 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817304 |
Product Specific Information
This antibody detects endogenous levels of MST3 only when phosphorylated at Thr18.
Target Information
STK24 (MST3) is a serine/threonine kinase belonging to the GCK subfamily of STE20-like proteins. The yeast Sterile 20 (STE20) gene functions upstream of the MAPK cascade. In mammals, STE20-related kinases are divided into two subfamilies:
- PAK subfamily: Contains a C-terminal catalytic domain and an N-terminal regulatory domain with a CDC42-binding domain.
- GCK subfamily (Sps1 subfamily): Contains an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain.
STK24 belongs to the GCK subfamily of STE20-like kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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