Thermo Fisher Scientific CD205 Monoclonal Antibody (HD30)
CD205 단백질을 인식하는 마우스 모노클로날 항체로, 인간 Lymphocyte Antigen 75 검출에 사용됩니다. Western blot, IHC(F), 유세포분석에 적합하며, 비결합형 액상 형태로 제공됩니다. 항원 특이적 T세포 면역 유도 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HD30 |
| Immunogen | Purified extracellular domain of human CD205-IgG1 Fc fusion protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2745109 |
Product Specific Information
Mouse anti-Human CD205 antibody, clone HD30 recognizes human Lymphocyte Antigen 75, also known as CD205, DEC205, C-type lectin domain family 13 member B, or gp200-MR6.
Target Information
CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking, and presentation, enhancing the induction of antigen-specific T cell immunity.
It is highly expressed by CD8+ dendritic cells (DCs) and also found in bone marrow Gr1+ cells, Langerhans cells, bone marrow-derived DCs (BMDCs), and thymic epithelial cells.
CD205 functions as an endocytic receptor that directs captured antigens to specialized antigen processing regions and can reduce proliferation of B lymphocytes.
Dysfunction of CD205 is associated with diseases such as pneumonic plague and lipid pneumonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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