Gibco™

BMPR1A Recombinant Human Protein

Bone Morphogenetic Protein Receptor 1A (BMPR1A) Fc Chimera is a bioactive protein intended for use in cell culture applications. BMPR1A자세히 알아보기

Bone Morphogenetic Protein Receptor 1A (BMPR1A) Fc Chimera is a bioactive protein intended for use in cell culture applications. BMPR1A is one of the bone morphogenetic protein (BMP) receptors which are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

• High purity—no interference from other proteins or contaminants
• High biological activity—more results with less protein
• Proven compatibility—Gibco™ proteins bioassayed with Gibco™ media

High Purity Recombinant Bioactive Protein
Bone Morphogenetic Protein Receptor 1A Fc Chimera is one of our more than 250 available Gibco™ recombinant proteins. To help ensure Gibco™ growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.

High Biological Activity
In-house activity testing of Gibco™ Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Bone Morphogenetic Protein Receptor 1A (BMPR1A) specific activity is determined by its ability to inhibit human BMP4induction of alkaline phosphatase in the mouse chondrogenic cell line ATDC5.

Proven Compatibility
Gibco™ proteins are bioassayed with Gibco™ media. Since 1962, Gibco™ has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.

See our selection of recombinant Gibco™ growth factors.

For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.

사양

등록 번호NM_004329

용도(애플리케이션)Cell Culture

유전자 ID(Entrez)BMPR1a

분자량43.7 kDa

정제 방법Sequential Chromatography

수량25 μg

유전자 별칭BMPR1A

생물학적 활성ED50 range = 0.1 to 0.3 μg/ml

종Human

재조합Recombinant

단백질 태그Untagged

분류Carrier-Free

엔도톡신 수준< 0.1 ng/μg

인디케이터 셀mouse chondrogenic cell line ATDC5

질량25 μg

반응성Human

배송 조건Wet Ice

특이 활성ED50 range = 0.1 to 0.3 µg/ml

발현 시스템Mammalian

단백질군Growth Factors & Receptors

단백질 형태Recombinant, Ligand, Fc Chimera

형태Lyophilized

단백질 아형BMPs (Bone Morphogenetic Proteins) & Related Factors

연구 카테고리Stem Cell Research, Neurobiology

제품라인Gibco™

순도 또는 품질 등급95 %

Unit Size25 µg