Thermo Fisher Scientific FNDC4 Monoclonal Antibody (OTI3B11), TrueMAB
Human FNDC4 단백질을 인식하는 mouse monoclonal antibody로, Western blot 및 Immunocytochemistry에 적합. 항염증 관련 연구용으로 사용 가능. Lyophilized 형태이며 PBS buffer에 trehalose 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B11 |
| Immunogen | Full-length human recombinant FNDC4 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
FNDC4 acts as an anti-inflammatory factor in the intestine and colon. It binds to macrophages to downregulate pro-inflammatory gene expression and affects macrophage functions such as phagocytosis. This regulation occurs partly via STAT3 activation and signaling. FNDC4 may help dampen immune responses during colitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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