Thermo Fisher Scientific Cyclin C Polyclonal Antibody
Cyclin C 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, Human, Mouse, Rat 반응성. 고순도 Affinity chromatography 정제 및 -20°C 보관 안정성.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CCNC (Accession P24863), corresponding to amino acid residues E249–S283 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818401 |
Product Specific Information
Antibody detects endogenous levels of total Cyclin C.
Target Information
Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knockout of the CLN genes in Saccharomyces cerevisiae.
Cyclin C is a nuclear protein present in a multiprotein complex and interacts both in vitro and in vivo with cdk8, a novel protein kinase of the cdk family.
It is suggested that Cyclin C and cdk8 control RNA polymerase II function. Human cdk8–Cyclin C might be functionally associated with the mammalian transcription apparatus, possibly involved in relaying growth regulatory signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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