Thermo Fisher Scientific Phospho-EphB1/EphB2 (Tyr778, Tyr780) Polyclonal Antibody
EPHB1/EPHB2의 Tyr778/Tyr780 인산화 상태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western blot과 Immunocytochemistry에 적합. 인간, 생쥐, 랫트 반응성. 고순도, -20°C 보관.
- 카탈로그번호
- PA5106133
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHB1 (Accession P54762), corresponding to amino acid residues around phosphorylated Tyr778 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817531 |
Product Specific Information
Antibody detects endogenous levels of EPHB1/2 only when phosphorylated at Tyr778/Tyr780.
Target Information
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system.
Based on their structures and sequence relationships, ephrins are divided into:
- Ephrin-A class: Anchored to the membrane by glycosylphosphatidylinositol linkage
- Ephrin-B class: Transmembrane proteins
The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase family.
The protein encoded by this gene is a receptor for ephrin-B family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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