Thermo Fisher Scientific IL-2 Polyclonal Antibody
인간 IL-2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, Flow Cytometry에 사용 가능. 고순도 항원 친화 크로마토그래피 정제. PBS/glycerol buffer에 보존되며 4°C 단기, -20°C 장기 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human IL-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.82 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792274 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Rhesus Monkey (97%).
- Positive Control: Raji.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7).
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for precise gene expression control.
Targeted disruption of an IL-2-like gene in mice leads to an ulcerative colitis-like disease, indicating its essential role in immune response to antigenic stimuli.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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