Thermo Fisher Scientific G6PD Polyclonal Antibody
Human G6PD 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P)에서 사용 가능. 고농도 액상 형태로 제공되며 Protein A로 정제됨. HepG2 세포를 양성 대조군으로 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human G6PD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 6.37 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792277 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Rat (90%), Rabbit (89%), Sheep (89%), Rhesus Monkey (98%), Bovine (89%).
- Positive Control: HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes glucose-6-phosphate dehydrogenase (G6PD), a cytosolic enzyme encoded by a housekeeping X-linked gene. Its main function is to produce NADPH, a key electron donor in defense against oxidizing agents and in reductive biosynthetic reactions.
G6PD exhibits significant genetic diversity, with many variants resulting from missense mutations that affect enzyme activity and clinical symptoms.
Deficiency in G6PD may cause neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been identified.
Caution
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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