Thermo Fisher Scientific MCP-1 Recombinant Superclonal Antibody (11HCLC)
Human MCP-1(CCL2) 타깃을 인식하는 Thermo Fisher의 Recombinant Superclonal™ Rabbit IgG 항체. 높은 감도와 특이성을 제공하며, Western blot과 ICC/IF에 적합. 재조합 시스템으로 로트 간 일관성 보장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific MCP-1 Recombinant Superclonal Antibody (11HCLC)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 2 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View publications |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 11HCLC |
| Immunogen | Recombinant protein corresponding to amino acids 24–99 of human CCL2 (MCP-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532516 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity and reproducibility of monoclonal antibodies.
Each Superclonal™ antibody lot contains a defined mixture of light and heavy chains, ensuring consistent performance across batches and eliminating biological variability typical of polyclonal production.
Formerly called “Recombinant Polyclonal Antibody”, this product is now branded as “Recombinant Superclonal™ Antibody” with identical physical and functional properties.
Target Information
The MCP-1 (CCL2) gene encodes a cytokine located on chromosome 17q. It belongs to the CXC chemokine family, characterized by two cysteines separated by a single amino acid. MCP-1 exhibits chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils.
It plays a role in inflammatory diseases with monocytic infiltration, such as psoriasis, rheumatoid arthritis, and atherosclerosis. MCP-1 binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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