Thermo Fisher Scientific c-Myc Recombinant Superclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:5,000
• View 2 publications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Recombinant rabbit Superclonal™ antibodies are composed of multiple recombinant monoclonal antibodies, combining polyclonal sensitivity with monoclonal specificity. Each lot is produced with a defined mixture of light and heavy chains, ensuring reproducibility and eliminating variability found in traditional polyclonal antibody production.
Formerly called “Recombinant polyclonal antibody,” now rebranded as “Recombinant Superclonal™ antibody.” Physical product and performance remain unchanged.

Target Information

The c-Myc protein (62 kDa) is a transcription factor encoded by the c-Myc gene on human chromosome 8q24. It is frequently activated in various tumor cells and plays critical roles in:

• Cellular proliferation and differentiation
• Apoptosis and cell cycle progression
• Vasculogenesis and angiogenesis in tumor development

Phosphorylation at Thr58/Ser62 by kinases such as GSK3, CDK, ERK2, and JNK regulates c-Myc activity.
c-Myc-, N-Myc-, and L-Myc-encoded proteins are involved in neoplastic diseases. Amplification or translocation of c-Myc is observed in multiple cancers, including lung, breast, colon, and Burkitt’s lymphoma.
Antibodies against c-Myc epitopes recognize overexpressed proteins containing Myc epitope tags at either terminus of target proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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