Thermo Fisher Scientific Transcription factor E3/TFE3 (Transcription Factor) Recombinant Rabbit Monoclonal Antibody (TFE3/6849R)
TFE3 전사인자에 특이적인 재조합 토끼 단일클론 항체로, 인체 시료에 반응합니다. IHC(P) 및 IHC(PFA)에서 사용 가능하며, 고순도의 Protein A/G 정제 항체입니다. PBS(pH 7.4) 버퍼에 보존제가 없으며, -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2 µg/mL
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TFE3/6849R |
| Immunogen | Recombinant full-length human TFE3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The activation of gene transcription is a multistep process triggered by transcription factors recognizing enhancer sites in DNA. These factors cooperate with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
The protein encoded by this gene is part of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is essential for SP1-mediated activation. It also participates in other multisubunit complexes such as thyroid hormone receptor-associated proteins, facilitating TR function on DNA templates in conjunction with initiation factors and cofactors.
This protein contains a bipartite nuclear localization signal and is known to escape chromosome X-inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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