Thermo Fisher Scientific Transcription factor E3/TFE3 (Transcription Factor) Recombinant Rabbit Monoclonal Antibody (TFE3/8663R)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

2 µg/mL

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

TFE3/8663R

Immunogen

Recombinant full-length human TFE3 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TFE3,uniProtId:P19532-1,ncbiNodeId:9606,antigenRange:1-575,antigenLength:575,antigenImageFileName:7030-RBM3-P1ABX_TFE3_P19532-1_Rabbit.svg,antigenImageFileNamePDP:7030-RBM3-P1ABX_TFE3_P19532-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.