Thermo Fisher Scientific BIK Polyclonal Antibody
Rabbit polyclonal antibody targeting human BIK protein. Validated for Western blot and immunocytochemistry. Supplied as liquid, unconjugated form purified by antigen affinity chromatography. Recommended storage at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in the amino-terminus of Bik |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977975 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other Bcl-2 family members.
Target Information
The Bik protein interacts with cellular and viral survival-promoting proteins such as BCL2 and Epstein-Barr virus to enhance programmed cell death. Its activity is suppressed in the presence of survival-promoting proteins, suggesting Bik as a likely target for antiapoptotic proteins. Bik shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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