Thermo Fisher Scientific Phospho-EphA8 (Tyr616) Polyclonal Antibody
Phospho-EphA8 (Tyr616) 폴리클로날 항체로, 인산화된 EPHA8 단백질을 특이적으로 검출. Western blot에 최적화된 고감도 항체. 인간 및 마우스 반응성. PBS/glycerol 버퍼에 보존되어 안정적이며 연구용으로 사용 가능.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA8 (Accession P29322), corresponding to amino acid residues around phosphorylated Tyr616 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817276 |
Product Specific Information
Antibody detects endogenous levels of EPHA8 only when phosphorylated at Tyr616.
Target Information
EPHA8 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors are involved in developmental processes, particularly in the nervous system. EPHA8 plays a role in short-range, contact-mediated axonal guidance during mammalian nervous system development. Receptors in the EPH subfamily typically contain a single kinase domain and an extracellular region with a Cys-rich domain and two fibronectin type III repeats. Ephrin receptors are classified into two groups based on extracellular domain sequence similarity and their binding affinities for ephrin-A and ephrin-B ligands.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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