Thermo Fisher Scientific FBXO8 Monoclonal Antibody (OTI7E12), TrueMAB
인간 FBXO8 단백질을 인식하는 Mouse IgG2a 단일클론 항체. Western blot에 최적화되어 있으며, 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적이며 PBS/BSA/glycerol 버퍼에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–231 of human FBXO8 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the F-box protein family characterized by an approximately 40 amino acid motif, the F-box.
F-box proteins are part of the SCF ubiquitin ligase complex (SKP1-cullin-F-box), functioning in phosphorylation-dependent ubiquitination.
They are divided into three classes:
- Fbws: Contain WD-40 domains
- Fbls: Contain leucine-rich repeats
- Fbxs: Contain various protein-protein interaction modules or no recognizable motifs
The FBXO8 protein belongs to the Fbxs class and contains a C-terminal region similar to yeast Sec7p, a regulator of vesicular protein transport.
It may interact with ADP-ribosylation factors (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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