Thermo Fisher Scientific FBXO8 Monoclonal Antibody (OTI3C5), TrueMAB
FBXO8 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot 및 IHC(P) 분석에 적합. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer에 보존. 인체 단백질 연구용으로 안정적이며 재현성 높은 결과 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–231 of human FBXO8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid motif called the F-box. F-box proteins form one of the four subunits of the ubiquitin protein ligase complex (SCFs: SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
F-box proteins are divided into three classes:
- Fbws containing WD-40 domains
- Fbls containing leucine-rich repeats
- Fbxs containing either different protein-protein interaction modules or no recognizable motifs
The protein encoded by this gene belongs to the Fbxs class and contains a C-terminal amino acid sequence similar to a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s) (ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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