Thermo Fisher Scientific beta-2, beta-2-Adrenoceptor Polyclonal Antibody
Rabbit polyclonal antibody targeting human beta-2 adrenergic receptor. Validated for Western blot applications. Supplied as liquid, 1 mg/mL concentration, purified by antigen affinity chromatography. Suitable for research use only, not for diagnostic p...
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from human beta 2 with the sequence GLRRSSKF. Target family: beta-2 Adrenergic Receptor (UniProt ID: P07550-1, NCBI Node ID: 9606, Antigen Range: 257–264, Antigen Length: 413) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine.
Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family.
Nine receptor subtypes have been identified, including:
- Alpha-1 AR subtypes: 1A/D, 1B, 1C
- Alpha-2 AR subtypes: 2A, 2B, 2C
- Beta AR subtypes: 1, 2, 3
ARs are involved in the onset or maintenance of several disease states, including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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