Thermo Fisher Scientific PLK4 Monoclonal Antibody (OTI2H5), TrueMAB
PLK4 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot에 최적화된 TrueMAB 제품입니다. Human 종에 반응하며, Lyophilized 형태로 제공됩니다. 고순도 Affinity chromatography 정제 및 안정적인 PBS buffer 구성으로 연구용에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H5 |
| Immunogen | Human recombinant protein fragment (aa 307–612 of human PLK4 produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PLK4 (Polo-like kinase 4) is a serine/threonine protein kinase localized to centrioles within centrosomes. It regulates centriole duplication during the cell cycle. Overexpression of PLK4 induces centriole amplification, while reduced gene dosage increases mitotic errors and cancer risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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