Thermo Fisher Scientific CD70 Monoclonal Antibody (OTI5D8)
CD70 단백질을 표적으로 하는 마우스 단클론 항체로, Flow Cytometry에 1:100 희석으로 사용 가능. 동결건조 형태로 제공되며, PBS 및 8% 트레할로스 완충액에 보관. 인간 CD70 단백질(HEK293T 유래)을 면역원으로 사용. 연구용으로만 사용 가능.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D8 |
| Immunogen | Full length human recombinant protein of human CD70 (NP_001243) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CD70 protein is a cytokine belonging to the tumor necrosis factor (TNF) ligand family and serves as a ligand for TNFRSF27/CD27.
It is expressed on activated T and B lymphocytes but not on resting cells.
CD70 induces proliferation of costimulated T cells, enhances cytolytic T cell generation, and contributes to T cell activation.
It also plays roles in B-cell activation, NK cell cytotoxicity, and immunoglobulin synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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