Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI5H1)

Applications

• Flow Cytometry (Flow)
  Tested Dilution: 1:100–1:400

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and plays a crucial role in cell-cell signaling, immune response regulation, and cell proliferation.
Mutations or dysregulation of ICOS have been associated with disorders such as Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.