Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI9H10)
Human ICOS 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 1:400 희석 비율로 사용 가능. Lyophilized 형태이며, PBS + 8% trehalose buffer에 보관. 세포 신호 및 면역 반응 연구에 적합.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9H10 |
| Immunogen | Full length human recombinant protein of human ICOS (NP_036224) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and plays a crucial role in:
- Cell-cell signaling
- Immune response regulation
- Cell proliferation control
ICOS is associated with disorders such as Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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