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Thermo Fisher Scientific Oncostatin M Monoclonal Antibody (17001)
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Oncostatin M 단백질을 인식하는 마우스 단클론 항체로, Western blot, ELISA, Flow cytometry, Neutralization 등에 사용 가능. 인간 시료 반응성, 비보존제 PBS 버퍼, 동결건조 형태로 제공. 연구용으로만 사용.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 03. 오전 04:28
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Thermo Fisher Scientific MA523810 Oncostatin M Monoclonal Antibody (17001) 100 ug pk판매 단위 pk ·
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551,400원VAT 포함 606,540원
Thermo Fisher Scientific · Thermo Fisher Scientific Oncostatin M Monoclonal Antibody (17001)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Flow Cytometry (Flow) | - | View 1 publication |
| ELISA (ELISA) | 0.1–0.4 µg/mL (Detection), 2–8 µg/mL (Capture) | - |
| Neutralization (Neu) | 0.5–2.0 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 17001 |
| Immunogen | E. coli-derived recombinant human Oncostatin M (Ala26–Arg234) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609439 |
Product Specific Information
- In ELISAs, this antibody does not cross-react with recombinant human IL-6, IL-11, CNTF, or LIF.
- Reconstitute at 0.5 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Oncostatin M (OSM) is a growth and differentiation factor involved in the regulation of neurogenesis, osteogenesis, and hematopoiesis.
Produced by activated T cells, monocytes, and Kaposi’s sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation.
- Stimulates proliferation of fibroblasts, smooth muscle cells, and Kaposi’s sarcoma cells
- Inhibits growth of certain normal and tumor cell lines
- Promotes cytokine release (e.g., IL-6, GM-CSF, G-CSF) from endothelial cells
- Enhances LDL receptor expression in hepatoma cells
- Shares structural and functional similarities with LIF, IL-6, and CNTF
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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