Thermo Fisher Scientific SLITRK1 Polyclonal Antibody
인간 SLITRK1 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체. Western blot에 적합하며, 신경세포 관련 단백질 연구에 활용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로 안정적 저장 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 450–675 of Human SLITRK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.62 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548697 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (99%), Rat (99%), Pig (99%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SLIT and NTRK-like family 1 (Slitrk1) belongs to a family of six homologous transmembrane proteins (Slitrk1–6) sharing two conserved leucine-rich repeat domains in the extracellular region and significant homology to Slit, an axonal growth-controlling protein. These proteins also show homology to trk neurotrophin receptors in their intracellular domains.
Expression of Slitrk proteins is restricted to neural and brain tumor tissues, with Slitrk1 mainly expressed in mature neurons. Overexpression of Slitrk1 induces unipolar neurites, whereas other family members inhibit neurite outgrowth, indicating a role in neurite regulation.
Variants of Slitrk1 have been suggested to be associated with Tourette’s Syndrome, though its involvement is considered minor.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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