Thermo Fisher Scientific NEUROD2 Monoclonal Antibody (3E7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

3E7

Immunogen

NEUROD2 (NP_006151.2, 266 a.a. approximately 375 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NeuroD2,uniProtId:Q15784-1,ncbiNodeId:9606,antigenRange:266-375,antigenLength:382,antigenImageFileName:H00004761-M01_NeuroD2_Q15784-1_House_mouse.svg,antigenImageFileNamePDP:H00004761-M01_NeuroD2_Q15784-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: RTHGYCAAYE TLYAAAGGGG ASPDYNSSEY EGPLSPPLCL NGNFSLKQDS SPDHEKSYHY SMHYSALPGS RPTGHGLVFG SSAVRGGVHS ENLLSYDMHL HHDRGPMYEE

Target Information

Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.