Thermo Fisher Scientific NEUROD2 Monoclonal Antibody (3E7)
NEUROD2 단백질을 인식하는 Mouse monoclonal antibody (Clone 3E7). Western blot 및 ELISA에 적합. 인간 시료 반응성. Affinity chromatography로 정제된 액상 제품으로, PBS(pH 7.4)에 보존제 없이 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- H00004761-M01
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- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E7 |
| Immunogen | NEUROD2 (NP_006151.2, 266 a.a. – approximately 375 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RTHGYCAAYE TLYAAAGGGG ASPDYNSSEY EGPLSPPLCL NGNFSLKQDS SPDHEKSYHY SMHYSALPGS RPTGHGLVFG SSAVRGGVHS ENLLSYDMHL HHDRGPMYEE
Target Information
Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription.
Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution.
Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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