Thermo Fisher Scientific NEUROG1 Monoclonal Antibody (2G4)
NEUROG1 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western Blot과 ELISA에 적합. 인간 시료 반응성, 액상 형태, PBS 버퍼에 보존제 없음. 신경발생 연구 및 세포 분화 관련 연구용으로 최적화.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2G4 |
| Immunogen | NEUROG1 (NP_006152, 82–163 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
SEALLHSLRR SRRVKANDRE RNRMHNLNAA LDALRSVLPS FPDDTKLTKI ETLRFAYNYI WALAETLRLA DQGLPGGGAR ER
Target Information
Neurogenin 1 (NeuroG1) is a basic helix-loop-helix (bHLH) transcription factor involved in determining cell type during development. It plays dual roles in cell-fate specification—promoting neurogenesis while inhibiting astrocyte differentiation. NeuroG1 acts as a transcriptional activator for neurogenesis and suppresses astrocyte differentiation by compartmentalizing the CREB-binding protein complex and inhibiting STAT transcription factors essential for gliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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