Thermo Fisher Scientific CD147 (soluble) Monoclonal Antibody (MEM-M6/1), PE

Applications

• Flow Cytometry (Flow)
  Tested Dilution: 20 µL / 1×10⁶ cells

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 488
• APC
• Biotin
• FITC
• Custom conjugation available upon request

Product Specific Information

This antibody recognizes an extracellular epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50–60 kDa type I transmembrane glycoprotein expressed on leukocytes, red blood cells, platelets, and endothelial cells. It is not expressed by resting lymphocytes.
The antibody exhibits high affinity and binds effectively to unstimulated peripheral blood T cells.

Target Information

CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF) is a 50–60 kDa glycoprotein with multiple glycosylated forms. It is a plasma membrane protein involved in spermatogenesis, embryo implantation, neural network formation, and tumor progression.
CD147 is part of the immunoglobulin superfamily and is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases and regulates integrin functions, contributing to cell development, activation, fetal development, and retinal function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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