Thermo Fisher Scientific IL24 Monoclonal Antibody (OTI3C5)
IL24 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(Paraffin)에 적합. 인체 반응성, 비결합형 액상 형태로 1 mg/mL 농도 제공. IL24 관련 JAK/STAT 신호 연구 및 암세포 성장 억제 메커니즘 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 52–206 of IL24 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723286 |
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein homologous to the interleukin 10 (IL-10) family of cytokines. Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors (IL-22R1/IL-20R2 and IL-20R1/IL-20R2), activating JAK/STAT signaling pathways. Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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