Thermo Fisher Scientific IL24 Monoclonal Antibody (OTI4E1)
인간 IL24 단백질을 인식하는 마우스 단클론 항체로, WB 및 IHC(P)에서 사용 가능. 고순도 친화 크로마토그래피 정제 및 PBS 기반 안정화 버퍼 제공. -20°C 보관, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 52–206 of IL24 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723287 |
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein belonging to the interleukin-10 (IL-10) cytokine family. Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds to two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2, leading to activation of the JAK/STAT signaling pathways. Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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