Thermo Fisher Scientific TOP2A Monoclonal Antibody (6C12G12)
TOP2A 단백질을 인식하는 Mouse monoclonal antibody로, Western blot, ICC/IF, Flow cytometry에 적합합니다. Human 및 Rat 시료에 반응하며, Protein G 정제 및 PBS buffer에 보관됩니다. 연구용으로 DNA 합성 및 세포 분열 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:200–1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C12G12 |
| Immunogen | Purified recombinant fragment of human TOP2A (aa 1100–1530) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898560 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Topo II alpha plays important roles in DNA synthesis and transcription, as well as chromosomal segregation during mitosis. It is a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells. Topo II alpha is also implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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