Thermo Fisher Scientific TLR9 Monoclonal Antibody (1B12H2)
TLR9 단백질을 인식하는 Mouse IgG2a 단클론 항체로, WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합합니다. 인간 시료 반응성이 있으며, Protein G로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific TLR9 Monoclonal Antibody (1B12H2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B12H2 |
| Immunogen | Purified recombinant fragment of human TLR9 (aa: 868–1016) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898557 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
The protein encoded by this gene belongs to the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns expressed on infectious agents and mediate cytokine production necessary for effective immune responses.
TLR9 is preferentially expressed in immune cell-rich tissues such as spleen, lymph node, bone marrow, and peripheral blood leukocytes. Studies in mice and humans indicate that this receptor mediates cellular responses to unmethylated CpG dinucleotides in bacterial DNA, triggering innate immune activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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