Thermo Fisher Scientific TOP2A Monoclonal Antibody (6D4B2)
Human TOP2A 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western Blot 및 IHC(Paraffin)에 적합. Protein G로 정제된 액상 형태이며 1 mg/mL 농도. DNA 합성 및 전사, 세포 분열 관련 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6D4B2 |
| Immunogen | Purified recombinant fragment of human TOP2A (aa: 1100–1530) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898559 |
Product Specific Information
This antibody has been tested in indirect ELISA.
Target Information
Topo II alpha plays important roles in DNA synthesis and transcription, as well as chromosomal segregation during mitosis. It is a sensitive and specific marker of late S-, G2-, and M-phases in transformed and developmentally regulated normal cells. Topo II alpha is also implicated in drug resistance of tumor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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